| The acute effects of quercetin consumption on arterial stiffness and heart rate variability in response to resistance exercise in type 2 diabetic patients |
| Paper ID : 1007-SPORTCONGRESS (R1) |
| Authors |
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Mohammad Javad Pour Ahmadi * Faculty of Sport Sciences and Health, Shahid Beheshti University, Tehran |
| Abstract |
| Background: Type 2 diabetes mellitus (T2DM) is strongly associated with arterial stiffness, autonomic dysfunction, and elevated cardiovascular risk. While resistance exercise is recommended for metabolic health, it may acutely increase arterial stiffness and blood pressure, particularly in diabetic individuals. Quercetin—a natural flavonoid found in various fruits and vegetables—has demonstrated antioxidant, anti-inflammatory, and vascular-protective properties that may attenuate such adverse responses. Objective: This study aims to examine whether acute supplementation with quercetin can modulate arterial stiffness and heart rate variability (HRV) responses following resistance exercise in men with T2DM. Methods: A randomized, double-blind, placebo-controlled crossover trial was conducted on 15 sedentary men aged 40–60 with controlled T2DM (HbA1c 6.5–8.5%). Participants consumed either 1000 mg quercetin (Jarrow, USA) or placebo (carboxymethyl cellulose) capsules three hours prior to performing a standardized resistance training session (6 multi-joint exercises, 3 sets, 10–12 reps, 70–75% 1RM). cfPWV and augmentation index (PulsePen), blood pressure (Omron M6), and HRV (Polar H10 + Elite HRV software) were assessed at baseline, immediately post-exercise, and 15 and 30 minutes afterward. After a one-week washout, participants repeated the protocol with the alternate supplement. Data will be analyzed using repeated measures ANOVA. Preliminary significance: This study will provide insight into the acute vascular and autonomic effects of quercetin in diabetic patients undergoing resistance training. Findings may help optimize supplement strategies to minimize cardiovascular strain during exercise in this vulnerable population. |
| Keywords |
| Type 2 diabetes, quercetin, arterial stiffness, blood pressure, heart rate variability, resistance exercise |
| Status: Abstract Accepted (Poster Presentation) |
