| The Effect of Moderate Aerobic Exercise on Inflammatory Markers in the Intestinal and Pancreatic Tissues of Obese Male Rats |
| Paper ID : 1331-SPORTCONGRESS |
| Authors |
|
Seyed ramin Rasooli *, Mandana Gholami, masoumeh mohamadkhani Department of Physical Education and Sport, Sciences,SR.C., Islamic Azad University, Tehran, Iran. |
| Abstract |
| Introduction: Obesity is a multifactorial disease that affects the quality and quantity of human health. Exercise has been considered an anti-inflammatory factor in individuals with overweight and obesity. Methods: Twenty-four male rats with an average weight of 220-250 grams were randomly selected and divided into three groups: healthy control (C), high-fat control (H), and high-fat + exercise (HT). The exercise program, conducted on a treadmill at a moderate intensity (55 to 65% of VO2max) corresponding to 20 meters per minute, was performed five sessions per week for five weeks. The expression of the IL-10 and TNFα genes was measured using Real-Time PCR. Data were analyzed using one-way ANOVA and Bonferroni post hoc tests with SPSS 2016 software, and a significance level of (P<0.05) was considered Results: The results showed that the expression of the IL-10 gene in intestinal tissue and the TNF-α gene in pancreatic tissue was significantly higher in the exercise group compared to the high-fat group (P = 0.001). Conclusion: The expression of the IL-10 gene increases, and TNFα decreases with exercise. Therefore, moderate-intensity aerobic exercise intervention has a significant impact on reducing inflammation. |
| Keywords |
| Obesity, Exercise, Inflammatory Markers. |
| Status: Abstract Accepted (Poster Presentation) |
