The effect of beta-alanine supplementation on systemic inflammatory status following high intensity functional training in young women
Paper ID : 1334-SPORTCONGRESS
Authors
Negin Ebrahimi *1, Hossein Mojtahedi2
1کارشناسی ارشد فیزیولوژی ورزش، دانشکده علوم انسانی، موسسه غیر انتفاعی هشت بهشت اصفهان، ایران MSc of Exercise Physiology, Hasht Behesht Higher Education Institute, Isfahan, Iran
2Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran
Abstract
Introduction: Beta-alanine, a non-essential amino acid found in the diet and produced through nucleotide catabolism, is important for muscle function. The aim of this study was to evaluate the effect of beta-alanine supplementation for 4 weeks on neuromuscular function and inflammation in individuals participating in high-intensity functional training (HIFT).
Methods: A randomized controlled trial included a total of 45 young, active female participants who were divided into three groups. The placebo group received sucrose powder plus HIFT, the beta-alanine group received beta-alanine powder plus HIFT, and the control group received sucrose powder without HIFT. The study lasted four weeks, during which the dose of beta-alanine + placebo consisted of 2 capsules of 800 mg for 4 times a day with intervals of more than 4 hours with meals for 28 days. The HIFT protocol was implemented for 4 weeks and 5 sessions per week with an intensity of 7-10 RPE and for 40-60 minutes for each training session. Blood sampling was performed to measure inflammatory factors before and after 4 weeks.
Results: The results of the mixed factorial analysis of variance showed that in the placebo group, 4 weeks of HIFT resulted in a modest decrease in resting levels of IL-6 (4.2 pg/mL to 1.3 pg/mL, p <0.05) and TNF-α (8.5 pg/mL to 6.7 pg/mL, p < 0.05) along with an increase in IL-10 (2.8 pg/mL to 3.9 pg/mL, p < 0.05). The beta-alanine group (4.6 g/day for 4 weeks) showed greater decreases in IL-6 (3.4 to 2.4 pg/mL, p < 0.01) and TNF-α (6.8 to 2.5 pg/mL, p < 0.01) and greater increases in IL-10 (7.2 to 1.5 pg/mL, p < 0.01) compared with placebo.
Conclusion: Overall, the present study showed that beta-alanine supplementation along with HIFT reduced fatigue caused by proinflammatory factors.
Keywords
Beta-alanine, high-intensity functional training, inflammation,
Status: Abstract Accepted (Poster Presentation)