| Optimizing Metabolic-Cognitive cross talk through exercise in eldery individuals with type 2 diabetes |
| Paper ID : 1398-SPORTCONGRESS |
| Authors |
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Zahra Raisi fiabadi *1, Ebrahim Banitalebi1, Mostafa Rahimi1, Majid Mardaniyan2 1Department of Sport Science, Shahrekord University, Shahrekord, Iran 2Department of Exercise Physiology, Faculty of Sport Sciences, Arak University, Arak, Iran. Research Institute of Applied Studies in Sports Sciences, Arak University, Arak, Iran. |
| Abstract |
| Abstract Background: Elderly with diabetes are at a high risk of cognitive impairment and Alzheimer disease (1). Exercise is a non-pharmacological disease modifying therapy for metabolic disorders such Diabetes (2). Also, exercise can improve cognition based on metabolic-cognitive cross-talk (3). The purpose of this study is to optimizing metabolic-cognitive cross-talk through exercise in elderly individuals with type 2 diabetes. Methods: In this randomized controlled trial 93 elderly with type 2 diabetes and mild cognitive impairment, randomly divided to high-intensity functional training (HIFT, N=31), low-intensity functional training (LIFT, N=31) and control (N=31) groups. Training group performed the 24 weeks of functional training 3 times/week. Metabolic (glucose, insulin, insulin resistance and glycated hemoglobin A (HbA1C) and Cognitive (processing speed, learning and memory) indices measured before and after intervention. Two-way ANOVA (group*time design) was used for between group comparisons. Result: Both exercise protocols had a significant improvement in glucose (P>0.007), insulin (P>0.055), insulin resistance (P>0.031) and serum HbA1C (P>0.001) and also processing speed (P=0.001), memory (p=0.001) and learning (p=0.001) compared to control group. Also, all indicators significantly improved in HIFT compared to LIFT (P>0.044) except insulin and learning (P≤0.05). Conclusion: According to the effect sizes, it is recommended to clinician to prescribe high intensity programs to reduce glucose, insulin resistance and improve serum HbA1C also learning, P>0.031 and memory in type 2 diabetic elderly with cognitive impairment. |
| Keywords |
| Functional Training, Exercise Intensity, Type 2 Diabetes, Elderly, Cognition. |
| Status: Abstract Accepted (Poster Presentation) |
