| Interactive Effect Of Eight Weeks Of Moderate-Intensity Aerobic Exercise And Cinnamon Supplementation On Serum Concentrations Of IL-17, IL-18 And IL-10 In Men With Metabolic Syndrome |
| Paper ID : 1542-SPORTCONGRESS |
| Authors |
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Hasan Naghizadeh * 2. Associate Professor of exercise physiology, Department of Sport Sciences, Ardakan University, P.O. Box 184, Ardakan, Iran. |
| Abstract |
| Introduction: Today, aerobic exercise and cinnamon consumption are considered one of the most effective non-pharmacological and non-invasive treatments for modulating inflammatory responses in people with metabolic syndrome. Therefore, the aim of the present study was to investigate the effect of eight weeks of moderate-intensity aerobic exercise and cinnamon supplementation on serum concentrations of IL-17,IL-18, and IL-10 in men with metabolic syndrome. Methods: For this purpose, 80 men with metabolic syndrome were selected based on the study entry criteria and randomly assigned to four groups: moderate-intensity aerobic exercise, moderate-intensity aerobic exercise with cinnamon supplementation, cinnamon supplementation, and placebo-control. The exercise was performed for 8 weeks(60-70% of heart rate reserve) and 3 sessions per week. Cinnamon supplementation(380 mg capsule, three times a day) was received for eight weeks. Blood samples were taken before the start of training and 48 hours after the last training session to measure serum concentrations of IL-17, IL-18, and IL-10. Data were analyzed using two-way analysis of variance with SPSS26 software. Results: The results showed that the interactive effect of training and cinnamon supplementation caused a significant decrease in serum levels of IL-17 and IL-18; and a significant increase in IL-10(p<0.05). Also, the main effect of training also caused a significant decrease in serum levels of IL-17 and IL-18; and a significant increase in IL-10(p<0.05). However, after eight weeks, the main effect of cinnamon supplementation did not cause significant changes. In addition, a significant difference was observed between the groups in terms of the means of IL-17,IL-18, and IL-10(p<0.05). The highest percentage of changes in IL-17,IL-18,and IL-10 were attributed to the exercise intervention combined with cinnamon supplementation. Conclusion: Performing moderate-intensity aerobic exercise combined with cinnamon supplementation has the greatest benefit in reducing serum levels of inflammatory markers and improving oxidative stress conditions in men with metabolic syndrome. |
| Keywords |
| Aerobic exercise, Cinnamon, Cytokines, Metabolic syndrome. |
| Status: Abstract Accepted (Poster Presentation) |
