The Effect of Resistance Training on Leptin Levels in Obese Individuals: A Review
Paper ID : 1605-SPORTCONGRESS
Authors
Neda Ebrahimpour *
M.Sc. in Applied Exercise Physiology, Azarbaijan Shahid Madani University
Abstract
Abstract: Obesity is a global health problem linked to type 2 diabetes, cardiovascular disease, and metabolic dysfunction. Leptin, mainly secreted by white adipose tissue, regulates appetite and energy expenditure. However, obese individuals often exhibit leptin resistance despite elevated leptin levels, impairing appetite regulation. Resistance training is a non-pharmacological approach that may enhance energy metabolism and modulate appetite-related hormones. Evidence suggests that it can influence leptin levels and sensitivity by decreasing fat mass, improving insulin sensitivity, and reducing inflammation, though results remain inconsistent. This review aims to clarify the effects of resistance training on leptin levels in obese individuals and identify key moderating factors.
Methods: A systematic search was performed in PubMed, Google Scholar, and Web of Science for studies published from 2000 to 2024, including clinical trials and reviews examining resistance training and leptin in overweight or obese populations. Extracted data included participant characteristics, exercise type and duration, and leptin-related outcomes. Results: Most studies indicate that resistance training reduces leptin levels and enhances leptin sensitivity, particularly when combined with dietary interventions. Exercise intensity, duration, and participants’ nutritional status were major determinants of the response. Conclusion: Resistance training, especially when paired with dietary control, appears to be an effective strategy for lowering leptin levels, improving leptin sensitivity, and supporting weight management in obese individuals.
Keywords
Resistance training, Leptin, Appetite hormones, Obesity
Status: Abstract Accepted (Poster Presentation)