| The effect of percooling during exercise in a hot environment on markers of liver damage |
| Paper ID : 1609-SPORTCONGRESS |
| Authors |
|
Marziyeh Gholami, Elham Vosadi *, Adel Donyaei Department of exercise physiology, Faculty of Physical Education and Sport Sciences, Shahrood University of Technology, Semnan, Iran |
| Abstract |
| Introduction: Exercise in a hot environment can lead to an increase in core body temperature and cause heat stress, which is associated with impairment of liver. The present study aimed to investigate the effects of exercise in a hot environment combined with percooling on liver injury markers in rats. Methods: In this experimental study, 32 male Wistar rats divided equally into 4 groups: control, exercise in a hot environment, exercise in a normal environment and exercise in a hot environment + percooling. After eight weeks of training and intervention, liver tissue was removed from the animal and gene expression levels AST and ALT were measured. Normality of data distribution was assessed using the Shapiro-Wilk test and homogeneity of variances was confirmed using the Levene test. Group comparisons were performed using ANOVA and the Bonferroni post hoc test. .Results: In the AST variable, the results showed a significant difference between the groups (p=0.001). There was a significant difference between the control group and the warm environment training groups (p=0.001), warm environment training + percooling (p=0.001), while the difference between the control and normal environment training groups (p=0.725) was not significant. In the ALT variable, the results showed a significant difference between the groups (p=0.001). The findings showed that there was a significant difference between the control group and all training groups (p<0.01), such that ALT gene expression increased in the training groups compared to the control. Although there was no significant difference between the normal environment training group and the other training groups (p>0.05), the warm environment training group showed a significant increase compared to the control (p<0.001). Conclusion: Exercising in a hot environment can lead to heat stress and liver damage, but the use of percooling plays an effective role in reducing these damages and improving physiological responses. |
| Keywords |
| local percooling, liver damage, hot environment, heat stress |
| Status: Abstract Accepted (Poster Presentation) |
